Workshops

During the International Gold conference 2022, several workshops will be offered by our sponsors, please click on the buttons below to have more information.

For your convenience, workshops registration is integrated into the registration process. As the number of attendees is limited, we strongly suggest you to book your place at the same time as you register for the GOLD 2022 conference.

Workshop 1: Novel Inline nanosizing method to support bottom-up process development and
manufacturing
- from InProcess LSP

***Acknowledgments to our Bronze sponsor!

Date: Monday, July 18, 2022, 12:00 to 13:00 (Free of charge; mandatory registration)

Title: Novel Inline nanosizing method to support bottom-up process development and
manufacturing

Description: With the rise of nanotherapeutics -and nano based products in general-, there has been an increasing need for better understanding and control of nano-particle (NP) synthesis and formulation processes. Size characteristics are often primary, if not critical, quality attributes of nanodispersions. Process Analytical Technology (PAT) tools for inline size characterization during dispersion processing are therefore highly desired. Traditional methods for NP sizing - based on Dynamic Light Scattering (DLS) – are typically ill-suited for direct inline application: (i) typical dispersion turbidities in process conditions often exceed by far the application limits for DLS (ii) agitation/flow typical for process conditions is incompatible with standard DLS and (iii) direct and convenient inline application requires a non-invasive PAT tool giving measurements on process relevant time scales.

In this paper, we describe a new non-invasive PAT instrument, the NanoFlowSizer (Besseling et al., 2019). This instrument is based on Spatially Resolved Dynamic Light Scattering (SR- DLS), a technique that combines low coherence interferometry with traditional dynamic light scattering, providing continuous, real-time, inline size and PSD characterization of concentrated and/or flowing nanodispersions in process environments. We will show several new examples of inline real-time monitoring using this instrument in different processes; showing the ability of this instrument to track, non-invasively, particle size changes at real time in undiluted, highly turbid nanosuspensions.

Besseling, R., Damen, M., Wijgergangs, J., Hermes, M., Wynia, G., Gerich, A., 2019. New unique PAT method and instrument for real-time inline size characterization of concentrated, flowing nanosuspensions. Eur. J. Pharm. Sci. 133, 205–213. https://doi.org/10.1016/J.EJPS.2019.03.024

About the speaker:

RaquelRaquel Arribas Bueno is an Application Specialist at  InProcess-LSP. She holds a PhD in Pharmaceutical Crystallization from the University of Limerick in Ireland and a degree in Chemical Engineering from the University of Valladolid in Spain.  She has several years of experience in solid state and colloid science.

 

Workshop 2: Good practices in DLS, NTA and zeta potential analysis - from Malvern Panalytical

***Acknowledgments to our Bronze sponsor!

Date: Monday, July 18, 2022, 16:30 to 17:30 (Free of charge; mandatory registration)

Title: Good practices in DLS, NTS and Zeta potential analysis

Description: This workshop is aimed towards basic and advanced users of light scattering (dynamic and electrophoretic) and nanoparticle tracking analysis techniques for particle characterization. It will focus on the basic principles of both techniques and best practices when performing measurements and data analyses.

About the speaker: Dr. Robert Cocciardi

Robert CocciardiDr. Robert Cocciardi has over 15 years’ experience in the field of infrared and near-infrared spectroscopy. He graduated with a Bachelor`s degree in Biochemistry in 1996 and in 2003 completed his Doctoral degree at McGill University in the Department of Food Science and Agricultural Chemistry with the McGill Infrared Group. After graduating, Robert continued to work with infrared spectroscopy as a post-doctoral fellow developing new methods for lubricant condition monitoring and then in 2007 was hired as a near-infrared applications scientist at Bruker Optics in Massachusetts. In 2011 Robert transitioned into sales of NIR spectrometers in Canada first as a representative for Bruker and then joined Analytical Spectral Devices (ASD), a division of Malvern Panalytical in 2016 where he managed sales of the FieldSpec, TerraSpec and LabSpec. Please join me in…

Workshop 3: Electron microscopy analysis of gold nanostructures - from SFR - Thermo

***Acknowledgments to our Bronze sponsor!

Date: Tuesday, July 19, 2022, 12:00 to 13:00 (Free of charge; mandatory registration)

Title: High resolution electron microscopy equipment, strategies and procedures for the study of gold nanoparticles and gold nanostructures

Description: An overview of electron microscopy tools and techniques used today for high-resolution characterization of gold nanoparticles and nanostructures. This talk will discuss capabilities of the modern equipment used today, the advantages and limitations of various imaging techniques, as well as go into detail on how the data is collected. Several strategies for improving transmission electron microscopy (TEM) data will be discussed, including sample preparation tips and tricks, working with beam-sensitive samples, and improving statistics with high-throughput analysis.

About the speaker: Lee Casalena, PhD

Lee CasalenaPrior to joining Thermo Fisher Scientific, Lee completed his PhD in Materials Science & Engineering under Prof. Mike Mills at The Ohio State University. His research focused on the thermo-mechanical effects of gold additions to common shape memory alloy systems, including structural and chemical characterization of novel secondary phase formations using transmission electron microscopy and various other techniques. Lee spent five years broadening his knowledge base while working as an Applications Scientist before moving into his current role of Senior Product Specialist for Materials Science TEM, based out of Portland, Oregon.

Workshop 4: Surface plasmon resonance measurements - from Affinité Instruments

***Acknowledgments to our Bronze sponsor!

Date: Wednesday, July 20, 2022, 12:00 to 13:00 (Free of charge; mandatory registration)

Title: Democratizing Surface Plasmon Resonance (SPR): how you can integrate SPR into your everyday lab

Description: Surface plasmon resonance (SPR) is considered a gold standard technique for drug screening and measuring biomolecular interactions in real-time in a label free environment. Traditionally, SPR technology is mainly found in large pharmaceutical companies with high-throughput and automation design in mind. As a result, SPR is seen as an inaccessible option, being complex and costly to operate. 
Affinité Instruments has made it its mission to offer portable, affordable, and easy-to-use SPR to enable all researchers to use it as an analytical tool in diverse fields. Applications can expand from life sciences to material and applied sciences. This workshop will dive into some of example applications in environmental monitoring, biosensing, protein and surface material characterization, point of care diagnostics as well as latest work on Adeno-Associated Virus (AAV) titer analysis. Plus, come experience a live demo of the portable SPR and hear our Affinité application scientist explain the value of having this accessible and versatile tool on providing quick and reliable SPR data anytime, anywhere.

About the speaker 1: Ludovic Live PhD

Ludovic LiveDr. Ludovic Live is an expert in surface plasmon resonance instrumentation and plasmonic material. After his Ph.D. in Chemistry with Dr. Jean-François Masson at l’Université de Montréal in 2012, Dr. Live worked as scientist with Xagenic, a molecular testing startup, and as policy advisor for the Ontario Government before joining Affinité Instrument in 2018. Since then, Dr. Live helped commercialize SPR instruments for R&D in the US, Europe and Asia. 
 
About Speaker 2: Rim Aly PhD

Rim AlyDr. Rim Aly holds a master’s degree and PhD in immunology and virology working extensively on AML and HIV clinical research studies at the Faculty of medicine of Alexandria University. She then joined the Division of Infectious Diseases at the Faculty of Medicine of the University of British Colombia to pursue her postdoc focused on early diagnosis of lung cancer. Currently, she works in a collaborative project with CERVO Brain Research Center of Université Laval and Affinité Instruments in expanding and integrating SPR technology as a rapid and reliable tool in AAV production and quality control.